Investing in Level Zero

We are excited to announce our investment in Level Zero’s Pre-seed round led by Red Alpine with participation from SOSV, Springbank, Unruly, Anorak, and others.

‍Level Zero is building the first-ever DNA-based hormone monitoring device, enabling access to the dynamic patterns of hormonal changes at an unprecedented level of granularity and accuracy, setting a new standard for hormonal monitoring and understanding.

Today’s hormonal health landscape is fragmented, inefficient, and reactive. For women going through delicate treatments like invitro fertilization (IVF), the process is particularly challenging. The status quo involves frequent, invasive, in person blood draws that are inconvenient and expensive.

Meanwhile, advances in biosensor technology are unlocking endless possibilities for non-invasive, real-time monitoring. Interstitial fluid (ISF) in particular, a medium already used in continuous glucose monitoring (CGM), has the promise to also enable tracking of hormonal data - something never seen before.

Enter Level Zero. Their wearable patch leverages ISF to measure key hormones such as cortisol, estrogen, progesterone, and testosterone with unprecedented accuracy. The results? A reliable, patient-friendly solution that enables greater physicians and patient insights into how hormonal levels fluctuate over time.

Level Zero is led by Ula Rustamova (CEO), a former enterprise tech lead at Palantir and Irene Jia (CTO), an R&D expert who has previously developed consumer medical devices for Phillips. Despite their varying backgrounds - Ula from Azerbaijan and Irene from China - they share a common story of resilience and deep passion for addressing the critical gaps in women’s health, an area that’s long been underserved. They’re still less than a year old and haven’t published any peer-reviewed papers (yet), but were selected as a top finalist for the Biomedical Catalyst Accelerator for Women's Health and TechCrunch’s Startup Battlefield - a testament to their pedigree and ambition.

We are very excited about Level Zero’s vision to redefine hormonal health monitoring, building a future where real-time insights empower greater health understanding, better care delivery, and improved health outcomes.

Black Jays Ventures is an early-stage VC fund investing in trusted products and services that address the modern needs of families.